5 abnormalities of normal breast tissue in the vicinity of cancers

báo cáo khoa học: "Sustained complete remission of human epidermal growth factor receptor 2-positive metastatic breast cancer in the liver during long-term trastuzumab (Herceptin) maintenance therapy in a woman: a case report" docx

báo cáo khoa học: "Sustained complete remission of human epidermal growth factor receptor 2-positive metastatic breast cancer in the liver during long-term trastuzumab (Herceptin) maintenance therapy in a woman: a case report" docx

Ngày tải lên : 11/08/2014, 02:22
... full remission in the liver but relapsed in the central nervous system within two months of withdrawal of trastuzumab maintenance therapy [9] Support for the importance of maintaining HER2 suppression ... of metastatic lesion in the liver taken in 2002 Page of Figure Magnetic resonance imaging scan taken in 2003 The hepatic lesion has disappeared of trastuzumab treatment during pregnancy and the ... that continuing anticancer treatments as maintenance therapy in patients in remission or with stable disease may prolong the disease-free interval [8] There is an increasing number of case reports...
  • 4
  • 211
  • 0
Báo cáo khoa học: " Herpes simplex virus type 1 and normal protein permeability in the lungs of critically ill patients: a case of low pathogenicity" docx

Báo cáo khoa học: " Herpes simplex virus type 1 and normal protein permeability in the lungs of critically ill patients: a case of low pathogenicity" docx

Ngày tải lên : 12/08/2014, 20:20
... Mallincrodt Diagnostica, Petten, The Netherlands), using a modified in vitro method Ten minutes after injection of the labelled RBCs, transferrin was labelled in vivo, following intravenous injection ... inflammation, of whatever cause, increases the PLI up to four times normal values in the most severe forms of lung injury, including ARDS In less severe injury, such as impending ARDS and interstitial ... withheld in the other two patients because it was presumed that the pulmonary infiltrates were not caused by HSV-1, on the basis of a normal PLI among other findings In patient 1, who had a normal...
  • 6
  • 284
  • 0
Effect of urban emissions on the horizontal distribution of metal concentration in sediments in the vicinity of Asian large cities

Effect of urban emissions on the horizontal distribution of metal concentration in sediments in the vicinity of Asian large cities

Ngày tải lên : 05/09/2013, 09:08
... number of samples taken in Korea In the case of Tokyo and in the Philippines, urban runoff from roads on rainy days contributes to the increase in metal concentration in the sediments of receiving ... samples taken in the eastern side of Manila Bay The concentration profiles in the sea sediments show the decrease in lead and zinc concentrations in the sediments with the increase in the distance ... on the uniform distribution of these metals in the sediments of the lake The higher concentration in the northwest part of the lake is probably due to reverse flow of the polluted Pasig River in...
  • 11
  • 440
  • 0
Báo cáo "Some results of discovering old vestiges in the vicinity of Kinh Thien Temple " doc

Báo cáo "Some results of discovering old vestiges in the vicinity of Kinh Thien Temple " doc

Ngày tải lên : 22/03/2014, 12:20
... N18.  In these  profiles,  the MRI  measuring  profile  with  178 distance of 1 m between the electrodes is profile  DIEN‐2  just  in front  of house  N15  and  the King’s yard and a plenty of the GPR measuring  ... structure  signs  along  these  profiles  coincide  with  each  other  and  are  at small depth (about 2.5 m) in the beginning of the profiles.  Fig. 4 presents the results of the GPR sections  with 200 MHz and 400 MHz antennae. All three  ... depth  of about 1 m and 2 m, existing from the beginning  to  the end  of the profiles.  Probably  these  two  foundation  layers  are  related  to  the culture  of the Le  Dynasty  and  the ...
  • 11
  • 231
  • 0
Báo cáo lâm nghiệp: "Evaluation of changes in the landscape management and its influence on animal migration in the vicinity of the D1 motorway in Central Bohemia" ppsx

Báo cáo lâm nghiệp: "Evaluation of changes in the landscape management and its influence on animal migration in the vicinity of the D1 motorway in Central Bohemia" ppsx

Ngày tải lên : 07/08/2014, 10:21
... anthropogenic pressure influencing the landscape structures in the vicinity of the linear construction in the form of a motorway, and especially due to the accompanying structures of linear or polygon ... and having service functions The individual images were fixed into a system of coordinates A line set on the layer modified in this manner designates the centre of the motorway within the investigated ... created that takes in 200 m on each side from the centre of the motorway and which stipulates the extent of the polygon in the area of interest In the polygon thus marked out, the individual biotopes...
  • 9
  • 353
  • 0
Báo cáo khoa học: "The micronucleus frequency in cytokinesis-blocked lymphocytes of cattle in the vicinity of a nuclear power plant" ppt

Báo cáo khoa học: "The micronucleus frequency in cytokinesis-blocked lymphocytes of cattle in the vicinity of a nuclear power plant" ppt

Ngày tải lên : 07/08/2014, 20:23
... tnalp rewop raelcun a raen detacol slamina neewteb stnuoc eht ni dnuof saw ecnereffid tnacifingis oN slamina eht fo etats lacigoloib lareneg eht etaulave ot demrofrep saw sisylana lacilototameH aera ... noitidda ni ,eroferehT snosaer lacihte suoivbo rof elbissopmi era snamuh ni serusopxe latnemnorivne level-wol ,cinorhc fo stceffe eht fo snoitagitsevni tceriD dleif eht ni deviecer evah smsinagro taht ... eht gnissessa rof elbatius si slamina larutlucirga ni snoitarreba lamosomorhc fo gnirotinom ehT tnemnorivne eht ni )snegotsalc rehto dna( sedilcunoidar ot erusopxe level-wol ,cinorhc morf ksir...
  • 4
  • 362
  • 0
Báo cáo y học: "Metastatic breast carcinoma in the mandible presenting as a periodontal abscess: a case report" pps

Báo cáo y học: "Metastatic breast carcinoma in the mandible presenting as a periodontal abscess: a case report" pps

Ngày tải lên : 10/08/2014, 23:21
... Figure Intra-oral view showing a diffuse swelling located over the buccal gingiva of the mandibular molar region and drainage of purulent exudate Page of in the mesial buccal aspect of the third ... eliminated the possibility of an endodontic-related lesion In the case presented herein, the location of the swelling, spontaneous intra-pocket suppuration and the existence of typical signs of ... are pain and tenderness of the affected area Drainage of purulent exudate from the periodontal pocket itself or from a fistula in the oral cavity is often noted Other findings include increased...
  • 5
  • 328
  • 0
Báo cáo y học: "Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue" doc

Báo cáo y học: "Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue" doc

Ngày tải lên : 09/08/2014, 03:24
... Synovial tissue from a patient with rheumatoid arthritis showing positive staining for Ang-1 (b) Positive staining in osteoarthritis synovial tissue (c) Ang-1 staining is absent in normal synovial tissue ... fibroblasts within the pannus, which are the putative target of this cytokine [18,19] The localization of Ang-1 is similar to that of VEGF, which further supports the crucial role of the interaction ... distributed in a similar pattern in RA and OA compared to normal synovial tissues (Fig 2) The dominance of Ang-2 over Ang-1 mRNA and protein in OA synovial tissue are in agreement with the inactive...
  • 9
  • 424
  • 0
Báo cáo khoa học: "The combination effect of sodium butyrate and 5-Aza-2''''-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines" pot

Báo cáo khoa học: "The combination effect of sodium butyrate and 5-Aza-2''''-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines" pot

Ngày tải lên : 09/08/2014, 04:21
... combined with 10% fetal bovine serum and 1% penicillin/streptomycin using a humidified cultivator that maintained 37°C and 5% CO2 The normal cell line was cultivated using the same cultivator in ... combination of SB and 5-aza-DC facilitates the transformation of chromatin into an activated state [8] In RKO cell lines, the effect of SB was similar to that of 5aza-DC, while in MCF-7 cell lines, ... cell lines In RKO cell lines, which are in a relatively hypermethylated state, the effect of 5-aza-DC was similar to that of SB; in MCF-7 cell lines, the effect of SB was better than that of 5-aza-DC...
  • 7
  • 327
  • 0
Báo cáo y học: " the Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer"

Báo cáo y học: " the Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer"

Ngày tải lên : 25/10/2012, 11:15
... surrounding cytoplasmic membrane in at least 10% of invasive carcinoma cells or presence of membranous staining in less than 30% provided that the staining is intense (++) Score 3: Presence of intense ... were included in the study Blood sampling was performed after surgery in the patients who were underwent surgical intervention (in group1 and 2) The serum samples in group were obtained after the ... groups The relevance of this finding is that it was the result of the first subgroup analysis for these biomarkers Bc1 should therefore be studied in terms of tumoral development and inflammatory...
  • 8
  • 584
  • 0
 Báo cáo y học: "Application of Small Angle X-ray Scattering (SAXS) for Differentiation between Normal and Cancerous Breast Tissue"

Báo cáo y học: "Application of Small Angle X-ray Scattering (SAXS) for Differentiation between Normal and Cancerous Breast Tissue"

Ngày tải lên : 02/11/2012, 11:08
... In order to study the effects of tissue storage upon the diffraction profiles measurements were made within 1.5 hours of harvesting and then repeated at intervals of two months during which the ... Int J Med Sci 2005 It was found that the total integrated intensity of coherent scattering from cancerous tissues is higher than that of normal adipose tissue This is similar to the finding of ... Ortec) The analyzer was used to digitize the analog information contained in each pulse, to process and store the data in memory and finally to display the contents of the processed data in the...
  • 4
  • 448
  • 0
Tài liệu Art of Surface Interpolation-Chapter 5:Solving special tasks In the next sections there are examples of interpolation problems, ppt

Tài liệu Art of Surface Interpolation-Chapter 5:Solving special tasks In the next sections there are examples of interpolation problems, ppt

Ngày tải lên : 21/01/2014, 07:20
... solving the wedging out of layer problem In the case of the first operation ($) the resulting value is the z-value of the first surface, but if the z-value of the second surface is greater, the ... resulting value is the average In the case of the second operation (%) the resulting value is the z-value of the second surface, but if the z-value of the second surface is greater than the z-value ... with linear interpolation method As pointed out in paragraph 1.2.1 Triangulation with linear interpolation, the domain of the triangulation method is restricted to the convex envelope of the points...
  • 17
  • 506
  • 0
Tài liệu Essentials of Psychiatric Mental Health Nursing in the BSN Curriculum: Collaboratively Developed by ISPN and APNA, (2007-2008) approved 5/08 ppt

Tài liệu Essentials of Psychiatric Mental Health Nursing in the BSN Curriculum: Collaboratively Developed by ISPN and APNA, (2007-2008) approved 5/08 ppt

Ngày tải lên : 14/02/2014, 13:20
... multidisciplinary and collaborative, Nursing has an integral role in affecting the mental health of millions of people through the use of unique skills, and by nature of the numbers of nurses who interact ... of Nursing and are beyond the scope of this document Given the critical role of nurses in all areas of health care, their ability to affect the emotional well being of clients regardless of the ... Somatoform disorders Family and community violence Use of informatics in psychiatric nursing Principles of teaching/learning theories as they relate to patients with psychiatric disorders including...
  • 13
  • 468
  • 0
Tài liệu Báo cáo khoa học: Novel aggregate formation of a frame-shift mutant protein of tissue-nonspecific alkaline phosphatase is ascribed to three cysteine residues in the C-terminal extension pdf

Tài liệu Báo cáo khoa học: Novel aggregate formation of a frame-shift mutant protein of tissue-nonspecific alkaline phosphatase is ascribed to three cysteine residues in the C-terminal extension pdf

Ngày tải lên : 19/02/2014, 17:20
... ubiquitinated in the presence of the inhibitor of proteasome function Furthermore, the extent of ubiquitination of TNSALP (1559delT) was further augmented in the cells expressing ubiquitin, strongly ... N-linked high-mannosetype oligosaccharide chains of glycoproteins [31] The involvement of EDEM and ⁄ or SCFFbs2 in the degradation of TNSALP mutant proteins is currently being investigated The ... growth, in turn controls mineralization According to this idea, increased levels of inorganic pyrophosphate resulting from the defect of TNSALP are thought to be the main cause of hypomineralization...
  • 14
  • 445
  • 0
Tài liệu Báo cáo Y học: Induction of (2¢)5¢)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide docx

Tài liệu Báo cáo Y học: Induction of (2¢)5¢)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide docx

Ngày tải lên : 21/02/2014, 15:20
... oligomers during 12 h synthesis Tissue from these animals was used to analyze if the endotoxin LPS has the capacity to induce the enzyme The data revealed that in the presence of lgÆmL)1 of LPS the (2–5)A ... Despite the initially high (2–5)A synthesizing activity in tissue of G cydonium (aquarium animals), the incubation with LPS caused significant increase of synthesis level (Table 2) The time course of ... course of the induction showed similarity to the effect we had seen in the case of S domuncula The increment of the products was highest on the third hour of incubation (1 lgÆmL)1 LPS) The most...
  • 11
  • 578
  • 0
Báo cáo khoa học: Hierarchical subfunctionalization of fabp1a, fabp1b and fabp10 tissue-specific expression may account for retention of these duplicated genes in the zebrafish (Danio rerio) genome docx

Báo cáo khoa học: Hierarchical subfunctionalization of fabp1a, fabp1b and fabp10 tissue-specific expression may account for retention of these duplicated genes in the zebrafish (Danio rerio) genome docx

Ngày tải lên : 07/03/2014, 12:20
... gradient in the levels of rat FABP1 mRNA is established in the intestine during the late fetal stage The mRNA concentration in the intestine increases sharply by three- to four-fold within 24 h of ... FABP1 during zebrafish embryogenesis The distinct patterns of expression for the fabp1b (in the intestine) and fabp10 (in the liver) genes in the developing zebrafish combined represent the expression ... that the insertion in the 5¢-UTR of the fabp1a gene occurred in zebrafish independent of other fish lineages Analysis of fabp1a and fabp1b genes in various fish species would likely resolve the timing...
  • 14
  • 554
  • 0
Báo cáo khoa học: Enzymes of mannitol metabolism in the human pathogenic fungusAspergillus fumigatus– kinetic properties of mannitol-1-phosphate 5-dehydrogenase and mannitol 2-dehydrogenase, and their physiological implications pot

Báo cáo khoa học: Enzymes of mannitol metabolism in the human pathogenic fungusAspergillus fumigatus– kinetic properties of mannitol-1-phosphate 5-dehydrogenase and mannitol 2-dehydrogenase, and their physiological implications pot

Ngày tải lên : 14/03/2014, 23:20
... residues for binding the coenzyme The C-terminal domain has a largely a-helical structure, and serves mainly in substrate binding The active site is located in the interdomain cleft, and contains a highly ... mm), and so the choice of the constant level of Fru was not critical for determination of DKm (1.23 0.15) The KIE data in Table are instrumental in delineating the kinetic mechanism of AfM1PDH ... value of $ 3, indicates that NADH binds to the enzyme prior to binding of Fru6P The absence of a KIE on kcat Km for the substrate binding rst is a clear requirement of the strictly ordered kinetic...
  • 13
  • 470
  • 0
Familial breast cancer - The classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care potx

Familial breast cancer - The classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care potx

Ngày tải lên : 15/03/2014, 00:20
... However, other family histories may also lead to a suspicion of an increased risk, due to the numbers of breast or other cancers in the family or in cases of bilateral cancer where each breast has the ... number of false positive results and the resulting increase in cost of those incorrectly brought back for further investigation In making any surveillance decision, the benefits and risks of each intervention ... contact if any of the following are present in the family history in addition to breast cancers in relatives not fulfilling the above criteria: • bilateral breast cancer • male breast cancer •...
  • 50
  • 462
  • 0
Báo cáo khoa học: Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family ppt

Báo cáo khoa học: Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family ppt

Ngày tải lên : 15/03/2014, 00:20
... their equivalents in the other subunit of the second dimer (Fig 4A) In the case of P21212 (TcRpiB-R5P), the four molecules in the asymmetric unit represent the tetramer The two active sites of ... stages in the biological cycle of the parasite (i.e the epimastigote and the metacyclic trypomastigote in the insect vector, and the intracellular amastigote and the bloodstream trypomastigote in the ... Arg141¢ The other end of the substrate points into a deep pocket in the enzyme Moving along the ligand from the phosphate, O4 interacts with His102¢ and a water molecule that is in turn within hydrogen-bonding...
  • 16
  • 401
  • 0